Biochemistry Department

Laura P. Schoepf Assistant Professor of Biochemistry Physical Biochemistry Molecular Endocrinology Biomedical Research Schoepf Research Group PubMed Citations Laura.Zanello@ucr.edu

Selected Publications

• Zanello, L.P., and Norman, A.W.  (2003) Molecular mechanisms of rapid 1a,25(OH)₂-vitamin D₃ multiple modulation of ion channel activities in osteoblasts. Bone 33: 71-79 
• Zanello, L.P., and Norman, A.W.  (2004) Rapid modulation of osteoblast ion channel responses by 1a,25(OH)₂-vitamin D₃ requires the presence of the functional vitamin D receptor. Proceedings of the National Academy of Sciences 101: 1589-1594
• Zanello, L.P., and Norman, A.W.  (2004) Electrical responses to 1a,25(OH)₂-vitamin D₃ and their physiological significance in osteoblasts. Steroids 69: 561-565
• Zanello, L.P., and Norman, A.W.  (2006) 1a,25(OH)₂-vitamin D₃ actions on ion channels in osteoblasts, Steroids, 71: 291-297
• Zanello, L.P., Zhao, B., and Haddon, R.C. (2006) Bone cell proliferation on carbon nanotubes, Nano Letters, 6: 562-567
•  Zanello, L.P. (2006) Electrical properties of osteoblasts cultured on carbon nanotubes, IEE Micro and Nano Letters, 1: 19-22
•  Zanello, L.P. (2006) Non-genomic mechanisms of vitamin D-regulated bone formation in osteoblasts, Clinical Cases in Mineral and Bone Metabolism, 3: 50-57
•  Zhang, X., Biswas, P., Owraghi, M., and Zanello, L.P. (2006) 1a,25(OH)₂-vitamin D₃ membrane-initiated calcium signaling modulates exocytosis and cell survival, Journal of Steroid Biochemistry and Molecular Biology, 103: 457-461
• Wu W., Zhang X., and Zanello, L.P. (2007) 1a,25(OH)₂-vitamin D₃ upregulates AP-1/p21^waf1 and inhibits human osteosarcoma cell proliferation via activation of MAPK pathways. Cancer Letters 254: 75-86
• Zhang X., and Zanello, L.P. (2008) Vitamin D receptor-dependent 1a,25(OH)₂ vitamin D₃-induced anti-apoptotic PI3K/AKT signaling in osteoblasts. Journal of Bone and Mineral Research 23:1238-1248
• Zanello L.P., Sharma P., Corzano R., and Hauschka P. (2008) Osteogenic induction on single-walled carbon nanotube scaffolds. NSTI Nanotechnology, 1: 75-78
• Zanello, L.P. Vitamin D and Cancer, in Encyclopedia of Cancer, 2009, Schwab M., ed., 2^nd   edition, Springer, NY. ISBN: 978-3-540-36847-2
• Biswas P., and Zanello L.P. (2009) 1a,25(OH)₂-vitamin D₃  induction of ATP secretion in osteoblasts. Journal of Bone and Mineral Research, 24: 1450-1460
• Bedi R.S., Beving D.E., Zanello L.P., and Yan Y. (2009) Biocompatibility and corrosion resistant of zeolite coatings for titanium alloy biomedical implants. Acta Biomaterialia, 5: 3265-3271
  
• Bedi R.S., Zanello L.P*., and Yan Y*. Zeolite MFI coatings on titanium alloy for bone tissue growth . Advanced Functional Materials, 2009,E-pub ahead of publication (* co-corresponding authors)
• Menegaz D., Barrientos-Duran A., Kline A., Silva F.R.M.B., and Zanello L.P. (2010) 1,25(OH)₂ Vitamin D₃ actions on chloride channels expressed in TM4 Sertoli cells. Journal of Steroid Biochemistry and Molecular Biology, 119: 127-134

Books (translations)

• Zanello L.P. and A.H. Rolan. Biology: Concepts and Relations, by Campbell, N.A., L.G. Mitchell, Reece, J.B., 3rd edition, 2000, Pearson Educacion Latinoamerica, Mexico, translated into Spanish from original English version, 860 pages.
• Zanello, L.P. Glossary for Biology, by Campbell, N.A., Reece, J.B., 8th edition, 2008, Benjamin Cummings Publishers, CA, translated into Spanish from original English version, 80 pages.
  
  

Selected Invited Talks 

• “1α,25(OH)2-vitamin D3 actions on chloride channels in osteoblasts”, 4th International Meeting on Rapid Responses to Steroids Hormones, San Diego, CA, March 2005
• “Vitamin D-regulated exocytosis in osteoblasts”, 45th Annual Meeting of the American Society of Cell Biology, San Francisco, CA, December 2005
• “Dissecting vitamin D3 nongenomic signaling in osteoblasts: Osteogenic functions of 1α,25(OH)2-vitamin D3”, invited talk at Boston Children’s Hospital, Harvard Medical School, Department of Urology, May 2006
• “Vitamin D3 nongenomic signaling in osteoblasts”, invited talk at University of Delaware, Department of Life Sciences, March 2007
• “Steroid-regulated signaling pathways in bone formation”, invited talk at the UCLA Human Genetics Speaker Series, University of California-Los Angeles, David Geffen School of Medicine, June 2007
• “Osteogenic actions of steroid hormones”, invited talk at the Department of Biological and Agricultural Sciences, Universidad de Veracruz-Xalapa, Mexico, September 2007
• “Bone regeneration on carbon nanotube scaffolds”, invited talk at the Department of Chemistry, California State University-San Bernardino, January 2009