Dr. Jeff Perry Receives $659,000 DOD Grant

grant will fund research to develop lead compound to treat breast cancer

Dr. Jeff Perry, Assistant Professor in the Department of Biochemistry has received a $659,000 grant from the Congressionally Directed Medical Research Programs of the US Department of Defense. Dr. Perry's lab will be partnering with a lab from the City of Hope as they have also received a grant from the CDMRP. 

You can read more about the grant and the research it is funding at the UCR News Article Here

From the UCR News Article:

Breast cancer totals 30% of newly diagnosed cancer cases; mortality rates are higher than all other forms of cancer except lung cancer. “Developing new breast cancer therapies is critical, as invasive breast cancer will strike about one in eight U.S. women during their lifetimes,” Perry said. 

This year, an estimated 268,600 new cases of invasive breast cancer and 62,930 new cases of noninvasive forms of the cancer are expected in women in the United States.

A big challenge for breast cancer researchers is developing more effective and less toxic treatment regimens for patients that also improve their chances of survival.

“Our goal is to bring to the clinic a novel lead compound that selectively targets breast cancer cells,” Perry said. 

His lab is focusing on AOH1160, a small molecule discovered at the City of Hope Medical Center that selectively kills many types of cancer cells through targeting proliferating cell nuclear antigen, or PCNA.


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